Search results for "Cell culture model"

showing 2 items of 2 documents

Macrophage type modulates osteogenic differentiation of adipose tissue MSCs

2017

Since the reconstruction of large bone defects remains a challenge, knowledge about the biology of bone healing is desirable to develop novel strategies for improving the treatment of bone defects. In osteoimmunology, macrophages are the central component in the early stage of physiological response after bone injury and bone remodeling in the late stage. During this process, a switch of macrophage phenotype from pro-inflammatory (M1) to anti-inflammatory (M2) is observed. An appealing option for bone regeneration would be to exploit this regulatory role for the benefit of osteogenic differentiation of osteoprogenitor cells (e.g., mesenchymal stem cells; MSCs) and to eventually utilize this…

0301 basic medicineHistologyMacrophageOsteoimmunologyAdipose tissueBone healingCell CommunicationBiologyBone morphogenetic protein 2Bone remodelingCell LinePathology and Forensic MedicineMSC03 medical and health sciencesCalcification PhysiologicAll institutes and research themes of the Radboud University Medical CenterOsteogenesisOsteogenic differentiationHumansBone regenerationCell ProliferationBone InjuryMacrophagesMesenchymal stem cellCell PolarityCell DifferentiationMesenchymal Stem CellsRegular ArticleCell BiologyAlkaline PhosphataseCoculture TechniquesCell biology030104 developmental biologyReconstructive and regenerative medicine Radboud Institute for Molecular Life Sciences [Radboudumc 10]Adipose TissueGene Expression RegulationCell culture modelImmunologyCytokinesBiomarkersCell and Tissue Research
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Decellularized Saphena: Biologic Scaffold for 3D Cellular Growth

2016

Settore MED/18 - Chirurgia GeneraleSettore BIO/13 - Biologia ApplicataSettore MED/22 - Chirurgia VascolareSettore MED/11 - Malattie Dell'Apparato CardiovascolareBioreactor Blood Vessels Cell Culture Models Regenerative Medicine Tissue Engineering
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